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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7489b417c5bf1ca0532d405836a3637712b8932217bb0c4366aa10421ac1f5d0' 
  AND token = 'x/0++NifFkUaIOi/O266g/3t1phUMsyHoErBZgBCrgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}