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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac5a94bd8ed52f40a01fac3c4b066cdb0fd65575351e02c2a1e3d151a80744d' 
  AND token = 'HLDP6MLIdX2N4purvwafQEEeTx8IcAasY6oxp8TgHa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}