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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df6287f7196d5a02214c5376e95e036e74b1665de6d01b4bf853ef2a2008d588' 
  AND token = 'yX8nuyt8Ohvgij47j5KxQcZpbedDBZ+aSB+Y9FXEh98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}