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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0d37b658651dcb15033eb91691e8f6fc988dd399cc175e0d50da98cd6f6e520' 
  AND token = 'aWHioy+ZzD8xJNLBT3kcdvWADc5XRllaTzRGFJbQ9mU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}