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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6456f534aaa2eb8af6b5c69c41eb8e39204ae984bd2c9331eed08be29038df3' 
  AND token = 'MCTUWKF8tsweB+tkXk7uFx6b7Dh9v9wiOVViGGrYWt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}