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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a729142c261a66d48731d5a92fd309c71a296b0aa53e7aeb8ed72573702b0c0a' 
  AND token = 'wHAcV442DBlKH1Fe4jFxA9DZ+5LrJaFGM1U4qiQ7778=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}