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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5db0ee19705c359ffe76e5b23170d3a362d0a19e24be8470a6aadc17a57f7f' 
  AND token = 'am6/QJKfJShYRoh8QU0WzrthK2bEj+4Y2qynU7Qa9D8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}