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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e132a047302d1a10f3269c6a739e1740c3732b65ac560e908a5d00047b20dac' 
  AND token = 'Mcx6395HbVH/0O0pxjHh225OFLxEZOQqGPW+Nc6f290=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}