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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c0b15015828d5c8115d5186f79a148d965d0171555bd95535adb78b61811235' 
  AND token = 'HpM01k2zmn5PJEiQz3c3/OqYJgmvUAPYTWrki9pz8LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}