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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535edf57d9c2119cfcdc7538326127610f2426ed35a4ab60b2e9037c5870d43f' 
  AND token = 'h2jBoaaA6ushVfhd4GxGZD1rN45RkJil4G2wSiBB/3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}