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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c661e2a6efa425027a430654dd2997478a0e08fbf7e17b8c36f9c78a4f0a48' 
  AND token = 'j/QJv1wZBALyicc9frR33u+ejBeZwKekOffG5VrftUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}