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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b1290f280338fedd2b2df6bccd962543b2cf537988b5f9c165ca0219c32337' 
  AND token = '3drfeIBJQM/t/6v5PtCoXwaqMjmrtkqQn7psZIo2nlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}