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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e16f65890a9d5fc22e14a7f95450db85ede31f0a216b5d49ac82b782d74e198' 
  AND token = 'IFa7V+289JhYuqBOL50a4+j0crCK4vA+nrE56gyplz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}