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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd397c04e04621fc2b41499501e1e744bfc6df3dce340aefeee655a40631005af' 
  AND token = 'uw7+Yb/6LBRm6uxQ1fmYk3vQLOso7C53hJuQcSc+xNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}