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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3cd26e7a0c2041c623e22075f00da46243390f2c2cc208b1baf409d4ae5c2d2' 
  AND token = 'J7zKw84CV7tZ3/Z8RxR0bY78gET+2Ks7r0hKVFlCx/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}