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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84202a1db55279ba07e5e2cd7cc40b3d118a6f86f0e0279448e778b6eb11d7af' 
  AND token = 'xX9I3/dpvfDjUGVau8EDOqqeN7pDYmjxr+uSuN93grU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}