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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74100c126b4e530fe75471e7d5505559d92cbf77208bad76383a4a416b37750c' 
  AND token = 'uPdux8yYZVIb3O9PXwj9N8sN1KThd9so1T7Ye43ohXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}