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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '259497ddce783935f01b8b0f5b3391dda949dce6df1a598d5a08be03471d590d' 
  AND token = '3sYyQkrYMg2vnh1yAT55jlT3U55vO6QkRv7WvLr4TDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}