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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e959e173f7a7e990958fd6205bee422b131a517739e6ad1a78e15502d09a59e3' 
  AND token = 'MNa0tf7fgK9O5qtP6RAe+BrQhW5Wbf1sITEoQQNt2+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}