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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8158ba2c4630d60c4789e592cf8b71156c883320d1427779f916af669b48fd9' 
  AND token = 'Q00AsaWcN79tSckobYdmPoc60z7qTdLjgNX3NCGXEGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}