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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a1d7b49e2af32b8870efb74392c737c44b45022c0f4f83c0309ca2505e2277' 
  AND token = 'cun+J/JMXptK3XtlFTlZ94EE2SUcBC6hm+dt1PizgUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}