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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2ff63a8198d6d6a8aa49d0226842b9830f07f6a574f613d38743fadd87370b' 
  AND token = 'uU1Z23+1SRAIuvsl4PqbCbCnZdooZH967LHmCfUvb5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}