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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8a6e96b51a1ddbb29145a1eb74e6b0de4c490a503e349900b5b22c7e96d5dd' 
  AND token = 'TtcHpLUW7rRo4sRth8MeuoAix20T8NT5cl35j7Rfyss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}