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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488ff1b8e583119fdf06c3fb8f57345c85dddab5bdb567f27caf5916497511cb' 
  AND token = 'QtSmCf6rI4aL1wG4M8qVH8pBePrSu/K3sa8N8LCNhI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}