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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68974c7d14f010a7c7426b38f07469e9189fafb4b46a6e260c7605d437b4fbe6' 
  AND token = 'dBKQr9mmBGNpUqDaI+KSYfC3NORh3xcK+j2SceC6OpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}