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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a0d0f0c4dd357eabbb3a83afc7806787a97453a1bcf7ef810d18466e06f210' 
  AND token = 'nDkIubwA19ug9RKxmI3q9wv+i4KHE90749x0yn2FieM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}