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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d46b9761ce463cc1fa5470961da2dff1f192bb401acba6e06bbdf16a2a5771' 
  AND token = 'iQ7vPIeLGx+Slz5IEXR9OpeyuWlm7mjm+BIo4LqcxDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}