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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad63be0a5415a3bab1bba2b04243a586d61f7bf2961e5f62aecd6ec10dd287c' 
  AND token = 'C7utIA2pf5+NdqZmhmF+2f9Day95e9VfUxwQXWOw0/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}