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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70e620a39f7c106d375c1e8f1eb838e8c016182664aec899fbd93399eaaa5caa' 
  AND token = 'PGagkWwHyJ6GMrWrBu5HYjBP83ypxsHcRc4Xe1nBwXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}