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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9efa32e93b06ce218415981b21853d1ba989e0b3334a1ec212ec84b2934a252c' 
  AND token = 'Wpp2YwgnjewLIKPAg3U3b+BI7wFNJIkiNiDTFDVpk9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}