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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b80433f3d279cdcec76b139bfe8c114f1989563284d053e1d848741720ef9b33' 
  AND token = 'kkZP2AVpi3bSVc2hX+N+spM6ZaKAYsip3pIYH3BP5eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}