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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8015a21b028ba9880f54e3f6f0910c940d723498bb0254536d9da76336b994d' 
  AND token = 'd5B4+NRnQ/dvyw7d4phd1pR8/pMhKjHOAD59MUdLsUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}