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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654a1af0670ee17394cbb7395f901c7cb9cd31b54e20f7796dda8ca65377630d' 
  AND token = 'PNLNlmiJIMNaeCDlcOukkNKENmF05mTNkeGPLR4P7lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}