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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '865291f25d0198ffc4472a92d2254ba00c0d110ac2a6ff6475855d26bb237030' 
  AND token = 'cnUlu9c1IoMI8EiO6X1Tla+vapgcWVfw1UxMNlvBnOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}