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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6be66e972eacf124ec096974121b5b0c0c16dd490c3e740638bd16f6dbf0f8a' 
  AND token = 'Qr+NZw34v9KBTs/OK9BUjIMtaJ2vVqIL5Qkj6xONc98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}