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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c164d32f6de39fcc4d47c073c2f7d81be2730eb8de3b1eedad174d0936c7c6e' 
  AND token = '+dBxhWbk6YCxmAs3EK1UWC9KRPJ6KAn0T4WrPvjMANs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}