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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756cf4aaa17e7cb73bad2930532aa4dc36eca69016ed423bd2501a3361acc8e2' 
  AND token = 'OTkwgjlGI7Mj499tCny/mUlgVHDJqXPQ/zLtro6BlnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}