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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353a2dc8349960ec5b708ec0b8e93fe17090711b06d3dbf5d596c2aac866dbe6' 
  AND token = '1Rpw27HBxduV5yXw4aSt5fA4cyVduRPJIj+aEQQN56Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}