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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afb3f193ceb4a6c6ffe7751a1cffa2a813080c83b05fc13bf0ffbefd043f547d' 
  AND token = 'h6filFB/m6uf1wlBgmH6pRtq2UwAMKuaUEbgbCwePYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}