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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a2cd6710792b8acadbf1c9b0231dfca19156d5fe2f6dfda0427ea5a81b8ee91' 
  AND token = 'DxFFccXCckgIn459WcD5R4gGeOR6rN32SdnIJei9VEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}