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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb0363af7d5e63539bd61040e422e864bda4af9db58649512ae70230085c86a5' 
  AND token = 'e2s3f247cYrL2/3lv/ISwwJc8g0XdYepdV3H2k+TbN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}