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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d7eea17a4aeb59c515b9ff1da2fc70425b2e95e8ffb716e65568b158ae9c016' 
  AND token = 'PHIBkcnNeCUwFn/yUCDB+ML6wd9+uaiQmGRQkH2ZPU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}