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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28e2d6f6a166a3e424c8d3a0b0b86d2ee6b9ab24c11868ca25a173b04f116070' 
  AND token = '1a3bjgAVW7ZOdl7k9xzPhcA67cXhjebsdD7sAAs286g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}