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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f646e6d7bba06a278072bcff8926e63722d47e59a9e44bdb6cd80fd8b3272ec' 
  AND token = 'Yxr+EPax47VHoKbPNoJLA+0TmlI2DOJl41mQoG4FNi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}