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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2cf349fe685999589c9b15099c2d672f8a5ee4bd474331a9c1eb1dfb45cb1b5' 
  AND token = 'YTPtvGP9EjuL0QZnPNrC+s1TM9mNI4wORsu8kJ3tnwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}