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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e895b0078f1ff11adf72650ff4a40a7e989303d768f3ba6da5ed1bd1da01aa1' 
  AND token = 'ndxeiIA53PJMyIa0ok8Ohy5X1pGHn4BtOvYXWGmiTzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}