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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4622a3047b4b726f836c1822443d361999278bee0f8899329dc7e7cdaed5ec66' 
  AND token = 'zuSQ8a7gbMq5wlE9IC4AOYVVlQu7yAe9bN3kj5v91WU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}