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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad4718eb95a30da80355c4b7e221ce5f2ef6b9057bff17c40a391202f21031c' 
  AND token = 'kXozZHYa0TvWdlWylwnDp9Sk3TivC9snJBI+AIqJAcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}