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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21fddb76320ea6948e64059f724ef1c7c2b7f31c206e0a7bed31e1033c0ef245' 
  AND token = '7BhhCl70QdPEb8YKkqnUEUodRpaS9Iy8fxrbpyOkaes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}