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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aa02b731f7b21a6cce9aa49b8f46db7d8f05f7b8799713f02cb0725c08946be' 
  AND token = 'pqM/aYCh6EWEBd0FQEuvXFt3NHHeNpbKR6+S48LdPWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}